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Concomitant use with metformin, sulfonylureas, dipeptidyl peptidase-4 (DPP-4) inhibitors, or insulin targets multiple pathways involved in glucose metabolism

This method bypasses the gastrointestinal tract and first-pass metabolism in the liver, potentially allowing for faster absorption and onset of action

Because GLP-1 drugs are expensive, can be difficult to access, and have significant side effects, many people have sought to increase their production of the natural hormone via nutritional modifications

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