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To determine the solution structural model of the p53 TAD2 -FOXO4-DRI complex using NMR spectroscopy, we recorded several sets of NMR experiments on two types of complexes: 13 C, 15 N-labelled p53 TAD2 -FOXO4-DRI and 13 C, 15 N-labelled FOXO4-LRI D -p53 TAD2 (see methods)
Tirzepatide: A dual GLP-1 and GIP receptor agonist that works across two metabolic pathways to help regulate hunger, insulin response, and weight loss outcomes
Dulaglutide (Trulicity): Given once a week, it improves blood sugar control
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