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International Journal of Clinical Practice, 64 (4), 497-504
These peptides act on the growth hormone axis, which is separate from testosterone
In large studies, GLP-1 therapies reduced body weight by an average of 4.57 kg, body mass index by 2.07 kg/m, and waist circumference by 4.55 cm compared with placebo
The same study confirmed dose-dependent increases in GH without significant changes in other pituitary hormones (prolactin, TSH, LH, FSH, cortisol), supporting its selectivity for the GH axis
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