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Generation of a HPV-16 E7 mutant with impaired ability to bind to GSTP1 Based on the docking model shown in Figure 3, we engineered the HPV-16 E7 sequence to obtain a mutant protein carrying alanine substitutions on residues predicted to be located at the interface of the interaction between E7 and GSTP1
In this review, we aim to summarize our current understanding of eryptosis, formulate a nomenclature and guidelines to interpret results of eryptosis studies, provide a synopsis of morphological and biochemical features of eryptosis, and highlight the role of eryptosis in health and disease, including its druggability
Glutathione is included for its effects on melanin synthesis
Z-stacks of 0.2 m step-size spanning a width of 5 m were taken to capture the most number of parasites per field of view, and maximum intensity projections were created in ImageJ (version 2.1.0/1.53c)
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