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The B6 formulation is neither better nor worse than alternatives in any clinically proven sense
Injection site reactions (redness, swelling, tenderness) are most common but typically resolve quickly
Maintaining optimal B12 levels helps ensure ongoing improvements in overall health and well-being
Currently, there is an ongoing randomised double-masked placebo-controlled trial, the SUMMIT trial, studying the efficacy and safety of tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide and GLP-1 receptors, versus placebo in HFpEF patients with obesity (NCT04847557)
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