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4.1 Revisiting classical pathways: context-dependent roles of Nrf2 and HDAC inhibition SFN activates the Nrf2 pathway through covalent modification of specific cysteine residues (Cys151, Cys273, and Cys288) on the Keap1 protein, leading to Nrf2 stabilization, nuclear translocation, and transcriptional activation of cytoprotective genes including NAD(P)H quinone oxidoreductase 1 (NQO1), heme oxygenase-1 (HO-1), and glutathione biosynthesis enzymes (6, 8)

The benzyl alcohol component is effective in limiting microbial growth, but concentrations are kept low (0.9%) to avoid altering compound stability under research conditions

27 The GHR also cross-talks and/or forms complexes with several other growth factor and hormone receptors (Fig

PMID 15618207