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Zepbound vs Wegovy Weight Loss Results Zepbound has demonstrated greater average weight loss in clinical trials compared to Wegovy: Zepbound led to as much as a 20.9% average reduction in body weight at the highest 15 mg dose over 72 weeks, according to results from the SURMOUNT-1 trial

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It is frequently studied alongside other peptide compounds in laboratory research environments

Zepbound (tirzepatide) is a once-weekly subcutaneous injection approved by the FDA for chronic weight management in adults with obesity or overweight with at least one weight-related comorbid condition