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The effect of thiamine and thiamine pyrophosphate on oxidative liver damage induced in rats with cisplatin
The efficacy of a second-generation derivative, omaveloxolone (RTA408), has recently been assessed in a preclinical model for diabetic chronic non-healing wounds [277] and, interestingly, omaveloxolone is now being tested in phase-II clinical trial for the Friedreichs ataxia (FRDA), a neurodegenerative condition in which NRF2 activation is suppressed [278, 279]
Choi, K.-C., Kim, S.-H., Ha, J.-Y., Kim, S.-T
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