Aetiology Current evidence suggests that around 85% of SJS/TEN cases are caused by medicine that is initiated in the preceding eight weeks of disease presentation, with the remaining cases being of unknown aetiology or, more uncommonly, Mycoplasma pneumoniae or herpes simplex virus (HSV) infections [3], [5], [6]
These can include nausea, vomiting, diarrhea, constipation, and bloating
5 Briefly, the conversion of dietary precursors into TMA involves four enzymatic pathways, including the choline-utilizing TMA lyase system (CutC/D), the carnitine Rieske-type oxygenase/reductase system (CntA/B), betaine reductase, and TMAO reductase
Impact on the Brains Reward System: GLP-1 receptor agonists, like Ozempic, interact with the brains reward system, which regulates appetite and pleasure