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Most GLP-1 side effects are mild and improve as your body adjusts
The pronounced HbA1c-lowering efficacy of GLP-1 agonist analogs in Asian patients has been attributed to several factors, primarily the observation that Asian patients with type 2 diabetes mellitus (T2DM) exhibit lower endogenous GLP-1 levels compared to their non-Asian counterparts [23]
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This doesn't mean GLP-1 therapy will fail, but it may suggest the need for higher doses, longer titration periods, or consideration of combination therapies like tirzepatide (dual GIP/GLP-1 receptor agonist) that engage additional pathways
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