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Subsequently, we discuss resistance patterns across different treatment modalities, including chemotherapy, targeted therapy, immunotherapy and hormonal therapy, and highlight emerging technologies and translational strategies to overcome resistance

Patients should also ask whether the program includes guidance on nutrition, hydration, exercise, and long-term maintenance

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Various authors have shown that serum ammonia concentrations directly correlate with the dose or serum concentrations of VPA, and inversely with serum concentrations of carnitine [22, 38, 39]