PubMed Jastreboff, A.M., Aronne, L.J., Ahmad, N.N., Wharton, S., Connery, L., Alves, B., et al
A population-based cohort study using administrative health data from British Columbia looked at NIDDM patients who also had an IMID (i.e., rheumatoid arthritis, psoriatic disease, ankylosing spondylitis, inflammatory bowel disease, or a systemic autoimmune rheumatic disease) and newly initiated a GLP-1-RA or dipeptidyl peptidase-4 inhibitors (DPP-4is) between 2010 and 2021
Subsequently, bioinformatic analysis revealed that innate and adaptive immune cells were associated with different mitochondrial metabolism pathways
Given her positive cardiolipin and beta-2-glycoprotein antibodies coupled with a clinical history of multiple unexplained spontaneous abortions and lack of embolic source, antiphospholipid antibody syndrome (APLS) was thought to be the most plausible explanation of the MRI findings