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Clinical trials have shown average weight losses of: Up to 15% of body weight with semaglutide (Wegovy) 1022% with tirzepatide (Mounjaro), according to JAMA But remember, these results were achieved with: Ongoing use of the medication Calorie-controlled diets Regular physical activity Behavioral support Some people choose to complement treatment with doctor-approved nutrition and lifestyle changes

5,6,7,8 MSM Supplementation decreases Oxidative Stress When supplemented with an average of 3895mg per day with MSM over the course of 10 days, 18 men undertook oxidative stress assessment after a 14 km run. MSM supplementation after exercise significantly increases GSH/GSSG ratio, a marker of antioxidant capacity and improves exercise recovery

This suggests that GLP-1 could suppress your appetite via direct, independent signaling in your brainnot just through your stomach

van Genderen AM, Jansen J, Cheng C, Vermonden T, Masereeuw R (2018) renal tubular- and vascular basement membranes and their mimicry in engineering vascularized kidney tubules