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Alzheimer's Research & Therapy (Review)
Obesity-associated adipose tissue thus functions as an inflammatory endocrine organ, particularly in visceral tissue producing TNF-, IL-6, IL-1, Monocyte chemoattractant Protein 1 (MCP-1, which is associated with tamoxifen resistance), and leptin while reducing adiponectin (an anti-inflammatory adipokine) levels, thereby promoting chronic low-grade inflammation, insulin resistance, and tumor-promoting signaling pathways
The visceral fat reduction alone translates to improved insulin sensitivity, reduced inflammation, and lower cardiovascular risk
In these cases, doctors may focus more on the persons weight, waist size, blood pressure, and blood test results
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