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The advantage of our test is, therefore, that it shows changes in GR activity not only due to higher/lower GR gene activity but also due to the absence of the reaction cofactor NADP
For most people, NAC is the smarter choice for boosting glutathione levels it's better absorbed orally, has decades of clinical evidence, costs less, and offers additional benefits like liver and respiratory support
(PMID: 34827486) and the broader systematic review by Ho and Nation (PMID: 29733881) provide some supporting evidence from outside the affected research group
The study was ultimately discontinued after five patients experienced fatal adverse events, including acute myocardial infarction, cardiac arrest, pneumonitis, and pleural effusion 92,93,94
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