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Gut microbiota as a mediator of cancer development and management: From colitis to colitis-associated dysplasia and carcinoma

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This dual mechanism reduces hunger intensity and calorie intake simultaneously, making it fundamentally different from older appetite suppressants

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Biochem Soc Trans 36:11201123

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Key lifestyle factors that support long-term results include: Stress regulation and nervous system balance Consistent, restorative sleep Strategic use of intermittent fasting when appropriate Regular resistance training to preserve muscle and insulin sensitivity A whole-food diet with adequate protein and balanced macronutrients Minimizing refined sugars, inflammatory seed oils, and excess alcohol When these foundations are neglected, appetite suppression alone may lead to short-term weight loss without improving metabolic resilienceor may even worsen body composition over time

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