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The guarantee allows users to trial the product with limited financial risk, understanding they can obtain refunds if results do not meet expectations

Tirzepatide activates both GLP-1 and GIP receptors, delivering average weight loss of 2022% in clinical studiesroughly 57 percentage points greater than semaglutide

Table 1 Changes in HbA1c, FPG, PPG, and weight from the randomized, head-to-head trials comparing GLP-1RA vs

orlistat, naltrexone/bupropion and phentermine) have a limited role in the management of overweight/obesity in people with or at high risk of CVD due to their minimal impact on weight, unknown CVD benefits and poor tolerability