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Children with Down syndrome have abnormal metabolic profiles and show increased incidence of a large number of serious diseases including leukemia and diabetes [61]
We speculate that the decreased level of 5-HT will lead to lower melatonin levels, and thus compromised antioxidant defenses, in patients
Bioavailability is a major hurdle for glutathione
Purity, sterility, and accurate dosing are major unknowns
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