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Some individuals who are highly sensitive to neuroactive peptides may prefer to begin slightly lower (100150 mcg) for the first few doses to assess tolerance before moving to the full protocol
One of the mechanisms that are currently investigated is the Wnt signalling pathway
A recent study showed that glucose metabolism was dysregulated and that pyruvate supplementation could prevent neurodegeneration in an animal model of glaucoma 31 , suggesting that ATP production from glycolysis is disrupted, and that other energy fuel pathways, such as -oxidation, may be augmented to compensate for the reduction in energy metabolism
E., Foresti, R
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