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Conversely, responders to ICB therapies exhibit increased antigen-presenting cell populations, aligning with studies that associate MHC class II (HLA-DR) molecule expression in melanomas with higher densities of CD8 + tumor-infiltrating lymphocytes (TILs) and favorable anti-PD-1 therapy responses (67, 68)
BPC-157 has been shown to upregulate epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), fibroblast growth factor-2 (FGF-2), and nerve growth factor (NGF) expression in multiple rodent tissue models
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