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Mice fed a high-fat diet (Western diet) present increased levels of cholesterol and triglycerides, with the activation of endoplasmic reticulum stress pathways in cardiac macrophages leading to the activation of inflammatory genes and affecting myocardial inflammation in heart failure with preserved ejection fraction (173)
PMID 16330153
NSAIDs, opioids and pregabalin, an anticonvulsant drug), or as hormonal therapies (24 hormone-dependant medications for cancers and contraception) offering short-term options to reduce pain by halting oestrogen production and endometrium growth
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