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PPs could decrease AFs-associated oxidative stress, genotoxic, mutagenic, and carcinogenic effects by improving cellular antioxidant balance, regulation of signaling pathways, alleviating inflammatory responses, and modification of gene expression profile in a dose/time-reliant fashion
194 Furthermore, aspirin induces ferroptosis, a form of cell death, by inhibiting NF-B p65-mediated transcription of SLC7A11, an inhibitor of ferroptosis
27 As in the case of tirzepatide, combining GLP-1 RAs with other enteropancreatic hormones holds promise for larger body weight reductions compared with GLP-1 RAs alone
Most remarkably, for almost all bacterial isolates, 30 mM GSH was shown to enhance antibiotic efficiency, indicating the practicality of GSH in treatment of biofilm-associated infections (Figure 2)
