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In the Lira Pump study, they decreased basal insulin by 10%, but increased bolus by 15% ( Our current practice is to consider a ~20% bolus insulin decrease and a ~10% basal insulin decrease before GLP-1RA initiation, although prior A1c, risk of hypoglycemia, potential risk of ketosis due to reduced insulin doses, as well as other patient-specific factors should guide the final insulin dose changes

Many patients prescribed Saxenda (liraglutide 3.0 mg) for weight management wonder whether the medication might affect their libido or sexual function

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A strongly reduced appetite can make it difficult to get enough protein, vitamins, and minerals