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These studies found no evidence of toxicity, organ damage, or concerning changes with chronic administration
Without adequate protein, metabolism can drop by 1520% during weight loss
Phase 2 trial data published in 2023 showed participants receiving the highest retatrutide dose lost an average of approximately 24 percent of body weight over 48 weeks, which exceeded results seen with dual-agonist medications in comparable timeframes
Int J Cancer 150:11341140
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