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Clearly, more intervention trials are urgently needed now to asses the effects of such substances as preventive or therapeutic agents in different populations and diseases, respectively

The biggest safety risk comes from using unregulated "research chemical" products rather than pharmaceutical-grade compounds from licensed pharmacies

Usually, the portal vein of such laboratory animals does not have culturable bacteria despite the presence of systemic sepsis, suggesting that BT takes place by transfer of intestinal bacteria predominantly into the lymphatic circulation via the intestinal lymph nodes, likely via the specialized M-cells overlying lymphoid aggregates [69, 70]

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