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A non-S1P-related drug which also appears to protect glial homeostasis is dimethyl fumarate (DMF)
Rodent research indicates that GLP-1 agonists may reduce dopamine release in the nucleus accumbens in response to alcohol, thereby potentially diminishing its rewarding properties
Available from: Filippatos TD, Elisaf MS
In one study, repeated topical 5% DHA application in hairless dogs led to irritant contact dermatitis, with histopathological findings of epidermal thickening, degeneration, and inflammatory changes, while vehicle-only controls showed no such effects, indicating DHA as the causative agent
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