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Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q

In short, various nanoparticles have been shown to exert anti-tumor immunity by directly targeting immune cell subtypes and thereby modulating multiple immune cells in the tumor microenvironment

Conjugation of alendronate to nanoparticle surfaces enables preferential accumulation at bone tumor sites, as demonstrated in multiple preclinical studies ( IL-11R represents another promising target for bone-specific drug delivery

49 They also discovered a drug called sonic agonist that mimics the effects of Shh and contributes to increased cerebellar growth in the DS mouse model