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Considering only events within various age groups, the ICERs indicated that SGLT2is were not cost-effective for people aged 1039 years or 4059 years for any intervention (although the ICER for SGLT2is in the secondary prevention population was 29,420), while SGLT2is were cost-effective among people aged 6079 years (ICERs of 28,002 and 328 in the primary prevention and secondary prevention populations, respectively) and 80 years, but GLP-1 RAs were not
Notably, the FDA authorized the medication for chronic weight loss in November 2023
In fact, studies show that many users lost 5% of their body weight in 12 weeks or less
This hormone slows gastric emptying, increases insulin secretion, and suppresses appetite through both peripheral and central mechanisms
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