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Retatrutide is a 39-amino-acid synthetic peptide that engages three metabolic receptors simultaneously: the GLP-1 receptor, the GIP receptor, and the glucagon receptor
Saxenda is a daily injection that may not be as effective for weight loss as Wegovy
However, it should be combined with lifestyle and diet changes
Both of these groups of medications have been shown to protect against heart disease and also progression of kidney dysfunction (primarily the SGLT2 inhibitors) that could lead to dialysis or transplantation
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