N Engl J Med 375:18341844 Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N, Maggioni AP, Marso SP, hman P, Pagidipati NJ, Poulter N, Ramachandran A, Zinman B, Hernandez AF (2017) EXSCEL Study Group

Here are the key benefits of using IGF-1 DES intelligently: Targeted Muscle Growth Because of its: High receptor binding affinity Ability to bypass IGF binding proteins Short half-life and local action IGF-1 DES is one of the best tools for: Targeting lagging muscle groups (arms, calves, chest, shoulders) Promoting localized hypertrophy Enhancing muscle fullness in trained areas When injected directly into the desired muscle group pre-workout , IGF-1 DES can drive: Rapid increases in fiber size Greater activation of satellite cells Improved vascularity and pump Localized administration of IGF-1 DES has been shown to stimulate targeted muscle hypertrophy and fiber remodeling through enhanced anabolic signaling. Philippou et al., Cell Communication and Signaling Accelerated Injury Repair IGF-1 DES is not just a bodybuilding peptide it is also one of the most effective agents for tissue regeneration and injury recovery

We and others also demonstrated that hemin induces the expression of NRF2 in SCD erythroblasts and animal models and such effect is mitigated by administration of dimethyl fumarate (DMF) 23,24 , an FDA-approved drug for the treatment of multiple sclerosis
The vial holds 5 mL, so at 0.2 mL a day it carries 25 doses, or five weeks of weekday injections