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This was corroborated by observations of embryonic lethality in mouse and Caenorhabditis elegans models, with oxidative stress damage shown to be the underlying cause (31)
Plasma levels of GHK-Cu are highest in young adults (approximately 200 ng/mL) and decline significantly with age (approximately 80 ng/mL by age 60)
however, differences in injection frequency, dose escalation, and device design meant that investigators were not blinded to which active treatment participants received [1]
