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Cannabinoid signaling and liver therapeutics
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The GLP-1RA liraglutide significantly reduces the eosinophilia and the production of type-2 cytokines species like IL-5 and IL-13 in the respiratory tract, while GLP-1R signaling downregulates innate allergic inflammation [135]
Extension studies reaching 4-5 years of continuous use show sustained efficacy with an acceptable safety profile
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