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Presented for research literature review only Ate NA et al

This phenomenon is associated with the overexpression of key enzymes, such as HMGCR, and transcription factors, including SREBP, involved in the cholesterol biosynthesis pathway (62, 64)

Isatinimino-acridinedione core 46 Diaryl triazole analogs have been shown to induce dual COX-2/TNF- inhibitory activities in previous studies (122, 123)