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Furthermore, CNS GIPR KO mice have a lower body weight than control mice
Possible side effects The most common side effects of Wegovy are digestive issues such as nausea, diarrhea, vomiting, constipation, indigestion and heartburn, gas and bloating, as well as headache, fatigue, dizziness, burping, runny nose or sore throat, and low blood pressure
These modifications can represent physiological adjustments to accumulated environmental exposure, altered metabolic demands, and changes in neuroendocrine sensitivity across the lifespan (Videnovic et al., 2014)
The mechanism involves direct action on pancreatic alpha-cells and potentially indirect effects through paracrine signaling within the islet microenvironment
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