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These two modalities can be linked through the concept of a provocative test. Because refractory migraine is a heterogeneous disorder, patients with centrally mediated or multifactorial pain syndromes (eg, related to prior craniotomies) are unlikely to benefit from peripheral MMA intervention

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Therefore, cross-comparison of findings demands careful consideration of these experimental parameters, and the future development of therapies would benefit from standardized models or studies explicitly designed to evaluate the impact of these variables on ferroptosis

kommt es zu einer Umwandlung von viszeralem, weissem Fettgewebe in thermogenes braunes Fettgewebe, was mit einem erhhten Energieverbrauch assoziiert ist (11)