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A 2024 retrospective analysis of 33,000 medical records of people with type 2 diabetes found patients who received the obesity drug Ozempic had roughly one-third to half the risk of overdosing on opioids compared to patients on other diabetes medications
Probiotic supplementation is generally beneficial for GLP-1 users experiencing constipation, particularly strains like Bifidobacterium lactis BB-12 and Lactobacillus rhamnosus GG that have demonstrated improvements in transit time and stool consistency
Given the heterogeneity among GLP-1RAs in terms of pharmacokinetic profiles, therapeutic efficacy, adverse event rates, and dosing regimens, each agent should be assessed individually
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