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It is unknown whether ZEPBOUND causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined [see Warnings and Precautions (5.1) and Nonclinical Toxicology (13.1)]
Trulicity was FDA-approved in 2014 after data from six unique clinical trialsincluding a total of 3,342 patientsrevealed that treatment with dulaglutide resulted in greater reductions from baseline in A1c levels compared with placebo. Is Trulicity (dulaglutide) approved for weight loss
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While no diabetic ketoacidosis or severe hypoglycemia occurred during any of the interventions, there were two episodes of recurrent euglycemic ketosis without acidosis during semaglutide use
