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Furthermore, IR in the liver and adipose tissue has been regarded as a crucial driver of NASH morbidity and mortality (120)
Clinical data from STEP and SURMOUNT trials show tirzepatide users achieved approximately 20-22% weight loss at highest doses, compared to semaglutide's 15-17% at comparable timepoints
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Semaglutide: approved and available (with caveats) Semaglutide has full FDA approval under two brand names
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