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Acknowledgments All the figures in this manuscript were drawn on www.biorender.com website
These tools therefore not only identify genetic regulators but also illuminate systems-level adaptation principles that can be therapeutically harnessed
However, long-term studies specifically tracking extended use are lacking
This elaborate transport mechanism highlights the absolute dependence of long-chain fatty acid -oxidation on carnitine availability, contrasting with medium-chain and short-chain fatty acids that enter mitochondria independently (24, 25)
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