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These metabolites also help to maintain epithelial and endothelial barrier integrity, which reduces systemic inflammation and the spread of microglial priming
In cardiovascular disease , a 2026 JACC abstract analyzing 233 major cardiovascular randomized controlled trials from 1986 to 2024 found average non-White representation of just 24.6% and, critically, no significant improvement in the 2020 to 2024 period compared with 1986 to 2019 ( [75] ) ( [76] )
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