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Seven reported relief lasting over six months
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Notably, bile acid signaling pathways can also contribute to OA pathology, as indicated by the alleviation of murine OA after suppression of farnesoid X receptor-the receptor for the bile acid glycoursodeoxycholic acid (GUDCA), which upregulates intestinal glucagon-like peptide-1 secretion (Yang et al., 2025)
This makes it particularly attractive for individuals using GLP-1 medications for weight loss
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