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The cleavage profile we observed for the protease was consistent with our observations of X(PC) in vitro cleavage, with procaspase-1 enriching in the top 97.8% of substrates (log 2 (fold enrichment) = 2.68) and IL-1 enriching in the top 83.5% of substrates (log 2 (fold enrichment) = 1.05
This pathway is considered to promote cell migration and adhesion, especially in tendon fibroblasts
DSIP is a naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) studied in sleep and neuroregulatory research
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