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Week 34 Many patients notice: Enhanced brightness Reduction in dullness More even complexion Week 58 Visible improvements often become more apparent: Better skin clarity Reduction in tanning Improved radiance Month 23 Most patients experience: Noticeable brightening Improved skin quality Better pigmentation control Month 36 Peak results may become evident with continued treatment and maintenance

Lower blood sugar and less hunger in combination result in improved metabolic health and decreased risk for diabetes

& Nonogaki, K

Despite the strength of this meta-analysis including a large cumulative sample size, exclusive use of RCTs, and comprehensive subgroup analysis some limitations must be acknowledged