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Clinical trials, including the SURMOUNT-5 study, demonstrate tirzepatides ability to achieve 13.7-20.2% weight loss in individuals with obesity but without type 2 diabetes, outperforming other GLP-1 receptor agonists in direct comparisons

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doi:10.5607/en22002

Evidence for metabolic dysfunction in ALS/ FTLD through omics and biochemical assays Mass-spectrometry based omics approaches present a great opportunity for a wide-scale and robust investigation of a pathophysiological link between neurodegenerative and metabolic processes in ALS/ FTLD