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We observed the presence of DLAT foci in the colons of patients with UC using immunofluorescence, implying the presence of abnormal protein oligomerization ( Figure 1F )
However, the risk of kidney disease should not be overlooked ( 2 Methods This systematic review of case reports was conducted and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement ( 2.1 Search strategies A comprehensive literature search was conducted using the PubMed/MEDLINE, Web of Science, Embase, the Cochrane Library, and CNKI databases to identify relevant case reports and case series published in English or Chinese from database inception to October 31, 2025
8 One similar study on a lower concentration (0.4% GHK-Cu) applied topically for venous statis ulcers, did not find benefit over placebo
