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Among the most pressing concerns is the emergence of nutrient insufficiencies, driven not by malabsorption per se, but by profound reductions in energy intake and food variety
Animal and Laboratory Research Preclinical research supports biological plausibility but cannot establish human treatment outcomes by itself
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282,283 Similarly, tirzepatide decreased left ventricular mass and paracardiac adipose tissue in patients with obesity-associated heart failure, corresponding with a reduced risk of heart failure events
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