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This combined approach might be especially helpful for individuals who have struggled to lose weight with diet and exercise alone or who have specific metabolic issues that make it difficult to lose weight
These data come from Cosmos, a dataset created in collaboration with a community of Epic health systems representing more than 304 million patient records from 2,000 hospitals and more than 47,000 clinics from all 50 U.S
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The lack of loss in fat mass could be due to the oscillatory weight loss in SEMA group attributed to the alternate day dosing, as opposed to previous studies where SEMA was administered daily 24,25,26
