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Mycotoxins such as ochratoxin, gliotoxin, and trichothecenes are known to: Disrupt lipid membranes Induce oxidative stress Alter immune signaling Affect central nervous system function In this case, both toxin burden and immune sensitization appeared to contribute to disease expression

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In a research context, the main limitations are the gap between animal and human data, stability sensitivity requiring proper storage, and the risk of compromised results if purity is not independently verified