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and indirectly, as the essential co-substrate for glutathione peroxidase (GPx) and glutathione S-transferase (GST) enzymes that detoxify hydrogen peroxide, lipid peroxides, and electrophilic compounds
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Although approved for diabetes, the drug is widely used off-label for weight loss because of its appetite-suppressing effects
As a result, we could not use the native H C domain to mediate receptor binding
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