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While GLP-1 and GIP receptor agonists modulate appetite and glucose regulation and show benefits in NASH, earlier agents have no direct effect on the liver fibrosis seen in more advanced disease
While both contain the same active ingredient, insurers are more likely to cover Ozempic for diabetes than Wegovy for weight managementeven though weight loss can significantly improve health outcomes
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The half-life means the drug accumulates to steady state over four to five weeks at a given dose
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